Case 11.3

In the intervening several months, the patient was seen in clinic for a mild flare of his ulcerative colitis managed with a short course of oral steroids.

Which statement regarding primary sclerosing cholangitis associated with inflammatory bowel disease is correct?
The majority of patients with IBD are affected by PSC
Only 8% patients with inflammatory bowel disease (IBD) are affected by PSC, however the majority (70-80%) of the patients with PSC have underlying IBD. All patients with a new diagnosis of PSC should undergo a colonoscopy.
PSC is more common in patients with Crohn’s disease
PSC is mostly associated with ulcerative colitis.
There is a predilection for left sided colitis
There is predilection for right sided colitis, rectal sparing and “backwash ileitis”.
IBD activity does not correlate with liver manifestations of PSC
IBD activity does not correlate with PSC liver disease.