Case 11.2
The patient underwent an MRCP which showed a beaded appearance reflecting multifocal stricturing of the extrahepatic and intrahepatic bile ducts consistent with primary sclerosing cholangitis. His repeat labs showed persistent elevation of alkaline phosphatase. He continues to be asymptomatic.
Which of the following is a poor prognostic indicator in patients with primary sclerosing cholangitis?
Female Sex
Male sex is associated with poor prognosis
Ulcerative Colitis
UC as compared Crohn’s disease has more progressive PSC
Normal IgG4 Level
Elevated IgG4 is associated with progression.
Small Duct PSC
Small duct PSC has a better prognosis as compared to large duct PSC.